In four areas of farmlands, hillside lands, greenbelts and lawns infected the red imported fire ants, Solenopsis invicta Buren, the efficiencies of Mieyiwei bait against S. invicta were investigated. The result showed that efficiencies of treatment after 10 days using this toxin bait were differed in these four infected areas, and all were relatively poor. However, 35 days later, they all showed excellent efficiencies. In which, the correction control effects against ant nests and worker termites in all the four infected areas attained to be more than 95%. This study indicated that the Mieyiwei bait was ideal to control the red imported fire ant in infected areas with varied ecological niches, however, the treatment time should be last for more than one month.