Subtropical Plant Science >

2026 , Vol. 55 >Issue 2: 169 - 175

DOI: https://doi.org/10.3969/j.issn.1009-7791.2026.02.004

Research articles

Protective Effect of Starch from Canna indica 'Edulis' against Acute Gastric Mucosal Injury in Mice

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  • (School of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529000, Guangdong China)

Received date: 2025-12-19

  Accepted date: 2026-02-05

  Online published: 2026-04-30

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Abstract

To investigate the protective effect of starch from Canna indica 'Edulis' (Jinshanyu) produced in Jiangmen, Guangdong Province, a mouse model of acute gastric mucosal injury was induced by hydrochloric acid-ethanol. By intragastric administration of Jinshanyu starch, the gastric index, gastric histopathology, gastric mucosal injury, serum lipid metabolism, and changes in oxidative stress levels in gastric tissue of mice were observed and determined. The results showed that, compared with the model group, the gastric index of mice in the Jinshanyu starch treatment groups were significantly increased, while the gastric mucosal injury index was significantly decreased. Specifically, the gastric mucosal injury score index of the high-dose Jinshanyu starch group was reduced to 2.70, with an injury inhibition rate as high as 60.51%. Histopathological results of gastric tissue indicated that the color and morphology of the gastric surface of mice in the Jinshanyu treatment groups gradually approached those of the normal group. In comparison with the model group, the length and width of the hemorrhagic bands were significantly reduced; meanwhile, gastric mucosal congestion, hemorrhagic injury, and inflammatory cell infiltration were significantly ameliorated, the injured area was markedly decreased, and the epithelial cell structure remained relatively intact. In addition, compared with the model group, the serum contents of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) in mice of the Jinshanyu treatment groups were significantly decreased, whereas the content of high-density lipoprotein cholesterol (HDL-C) was significantly increased. Moreover, the activities of total superoxide dismutase (SOD) and reduced glutathione (GSH) in gastric tissue were notably elevated. In conclusion, Jinshanyu starch exerts a protective effect against acute gastric mucosal injury in mice by improving the oxidative stress status of gastric tissue induced by hydrochloric acid-ethanol, regulating lipid metabolism disorders, and synergistically alleviating gastric mucosal hyperemia, hemorrhage, and inflammatory damage. This finding provides a scientific basis for the development of Jinshanyu starch-based products targeting gastric mucosal injury protection.

Key words： Canna indica 'Edulis' (Jinshanyu) starch; acute gastric mucosal injury; protective effect

Cite this article

XU Qin-yan, LIANG Cui-ting, WANG Wen-feng, LONG Jin-ting, JIA Xue-chong, LI Peng-fei, LI Dong-li, ANG Song . Protective Effect of Starch from Canna indica 'Edulis' against Acute Gastric Mucosal Injury in Mice[J]. Subtropical Plant Science, 2026 , 55(2) : 169 -175 . DOI: 10.3969/j.issn.1009-7791.2026.02.004

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