[1] 蒋小岗,顾振纶. 半枝莲的化学成分和药理作用[J]. 中国野生植物资源, 2004,23(1): 3—5.
[2] 何福根,章红燕,沈斌. 半枝莲抗肿瘤作用及其机制研究进展[J]. 中国肿瘤, 2008,17(2): 108—112.
[3] 肖海涛,李铣. 半枝莲的化学成分[J]. 沈阳药科大学学报, 2006,23(10): 637—640.
[4] 任强. 半枝莲化学成分及药理作用研究进展[J]. 济宁医学院学报, 2014,37(3): 157—161.
[5] 王兆全. 半枝莲化学成分的研究简报[J]. 中草药, 1981,12(2): 19—19.
[6] Tomimori T, Miyaichi Y, Imoto Y, Kizu H, Suzuki C. Studies on the constituents of Scutellaria species. IV. On the flavonoid constituents of the root of Scutellaria baicalensis Georgi (4)[J]. Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan, 1984,104(5): 529.
[7] Lin C C, Shieh D E. In vivo hepatoprotective effect of baicalein, baicalin and wogonin from Scutellaria rivularis[J]. Phytotherapy Research, 1996,10(8): 651—654.
[8] Zhang C, Zhang Y, Chen J, Liang X. Purification and characterization of baicalin-β-d-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge[J]. Process Biochemistry, 2005,40(5): 1911—1915.
[9] Li Y, Ooi L S, Wang H, But P P, Ooi V E. Antiviral activities of medicinal herbs traditionally used in southern mainland China[J]. Phytotherapy Research, 2004,18(9): 718—722.
[10] 向仁德,郑今芳,姚志成. 半枝莲化学成分的研究[J]. 中草药, 1982,13(8): 9.
[11] Chou C, Rivularin, a new flavone from Scutellaria rivularis[J]. Journal of Taiwan Pharmacists Association, 1978,30: 36—43.
[12] 余群英,张德武,戴胜军. 半枝莲化学成分的分离与鉴定[J]. 中国现代中药, 2011,13(002): 25—28.
[13] Tomimori T, Miyaichi Y, Imoto Y, Kizu H. Studies on the constituents of Scutellaria species (VIII): On the flavonoid constituents of ' Ban Zhi Lian', the whole herb of Scutellaria rivularis WALL(2)[J]. Shoyakugaku Zasshi, 1986,40(4): 432—433.
[14] Tomimori T, Miyaichi Y, Imoto Y, Kizu H. Studies on the constituents of Scutellaria species. V: On the flavonoid constituents of 'Ban Zhi Lian', the whole herb of Scutellaria rivularis WALL(1)[J]. Shoyakugaku Zasshi, 1984,38(3): 249—252.
[15] 刘英勃. 半枝莲提取工艺及化学成分研究[D]. 北京: 首都师范大学硕士学位论文, 2005.
[16] Lin Y, Chou C. Studies on the constituents of aerial parts of Scutellaria rivularis Wall[J]. Kuo Li Chung Kuo Yan Yen Chiu So Yen Chiu Pao Kao, 1984(7): 141—143.
[17] Wang G, Wang F, Liu J K. Two new phenols from Scutellaria barbata[J]. Molecules, 2011,16(2):1402—1408.
[18] Tomimori T, Miyaichi Y, Imoto Y, Kizu H, Namba T. Studies on nepalese crude drugs. V: On the flavonoid constituents of the root of Scutellaria discolor[J]. Chemical and Pharmaceutical Bulletin, 1985,33(10):4457—4463.
[19] 王文蜀,周亚伟,叶蕴华,杜楠. 半枝莲中黄酮类化学成分研究[J]. 中国中药杂志, 2004,29(10): 957—959.
[20] Tomimori T, Imoto Y, Miyaichi Y. Studies on the constituents of Scutellaria species. XIII. On the flavonoid constituents of the root of Scutellaria rivularis Wall[J]. Chemical and Pharmaceutical Bulletin, 1990,38(12): 3488—3490.
[21] Li P, Zhang G G, Zuo T T,Wang S C. Chemical constituents of the whole plant of Scutellaria barbata D. Don [J]. Journal of Shenyang Pharmaceutical University, 2008,7: 009.
[22] Miyaichi Y, Imoto Y, Tomimori T, Lin C C. Studies on theconstituents of Scutellaria species. IX.: on the flavonoid constituents of the root of Scutellaria indica L.[J]. Chemical and Pharmaceutical Bulletin, 1987,35(9): 3720—3725.
[23] Lin Y L, Kuo Y H, Cheng M C, Wang Y. Structures of scutellones D and E determined from X-Ray diffraction, spectral and chemical evidence. neoclerodane-type diterpenoids from Scutellaria rivularis Wall[J]. Chemical and Pharmaceutical Bulletin, 1988,36(7): 2642—2646.
[24] Sonoda M, Nishiyama T, Matsukawa Y, Moriyasu M, Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine[J]. Journal of Ethnopharmacology, 2004,91(1): 65—68.
[25] 乔春峰,韩全斌,宋景政,戴晋,莫世甫,徐宏喜. RP-HPLC测定半枝莲药材中4种主要黄酮类成分的含量[J]. 中国药学杂志, 2006,41(17): 1342—1344.
[26] Lin Y L, Kuo Y H, Lee G H, Peng S M. Scutellone A, a novel diterpene from Scutellaria rivularis[J]. Journal of chemical ResearchSynopses, 1987(10): 320—321.
[27] Dai S J, Peng W B, Shen L, Zhang D W, Ren Y. New norditerpenoid alkaloids from Scutellaria barbata with cytotoxic activities[J]. Natural Product Research, 2011,25(11): 1019—1024.
[28] Lin Y, Kuo Y H. Scutellone C and F, two new neoclerodane type diterpenoids from Scutellaria rivularis[J]. Heterocycles, 1988,27(3): 779—783.
[29] Dai S J, Peng W B, Shen L, Zhang D W, Ren Y. Two new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities[J]. Journal of Asian natural Products Research, 2009,11(5): 451—456.
[30] Wang F, Ren F C, Li Y J, Liu J K. Scutebarbatines W—Z, new neo-clerodane diterpenoids from Scutellaria barbata and structure revision of a series of 13-spiro neo-clerodanes[J]. Chemical and Pharmaceutical Bulletin, 2010,58(9): 1267—1270.
[31] Lin Y L, Guo T X. Four new neocledane-type diterpenoids, scutellones B, G, H, and I, from aerial parts of Scutellaria rivularis[J]. Chemical and Pharmaceutical Bulletin, 1989,37(3): 582—585.
[32] Dai S J, Wang G F, Chen M, Liu K, Shen L. Five new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities[J]. Chemical and Pharmaceutical Bulletin, 2007,55(8): 1218—1221.
[33] Kizu H, Imoto Y, Tomimori T, Kikuchi T, Kadota S, Tsubono K. Studies on the constituents of Scutellaria species. XVIII. structures of neoclerodane-type diterpenoids from the whole herb of Scutellaria rivularis Wall[J]. Chemical and Pharmaceutical Bulletin, 1997,45(1): 152—160.
[34] Wang Z Q, Xu F M, Yan X Z, Zhu Y. Scutebarbatine A, a new neoclerodane-type diterpenoid alkaloid from Scutellaria barbata[J]. Chinese Chemical Letters, 1996,7(4): 333—334.
[35] Dai S J, Tao J Y, Liu K, Jiang Y T, Shen L. Neo-clerodane diterpenoids from Scutellaria barbata with cytotoxic activities[J]. Phytochemistry, 2006,67(13): 1326—1330.
[36] Dai S J, Chen M, Liu K, Jiang Y T, Shen L. Four new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities[J]. Chemical and Pharmaceutical Bulletin, 2006,54(6): 869—872.
[37] Nie X P, Qu G W, Yue X D, Li G S, Dai S J. Scutelinquanines A–C, three new cytotoxic neo-clerodane diterpenoid from Scutellaria barbata[J]. Phytochemistry Letters, 2010,3(4): 190—193.
[38] Dai S J, Liang D D, Ren Y, Liu K, Shen L. New neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities[J]. Chemical and Pharmaceutical Bulletin, 2008,56(2): 207—209.
[39] Zhu P, Liu G. Isolation and identification of the diterpenoid and flavone in Scutellaria barbata D Don[J]. Journal of Plant Resour. Environ, 1993,2(4): 63—64.
[40] Yu J, Lei J, Yu H, Cai X, Zou G. Chemical composition and antimicrobial activity of the essential oil of Scutellaria barbata[J]. Phytochemistry, 2004,65(7): 881—884.
[41] 许益民,郭立伟,陈建伟. 半枝莲多糖的分离纯化及其理化性质[J]. 天然产物研究与开发, 1992,4(1): 1—5.
[42] 孟延发,李志孝,张立,陈耀祖. 半枝莲多糖 SPS4 组分的纯化性质及分析[J]. 生物化学杂志, 1993,9(2): 224—228.
[43] Ducki S W, Hadfield J A, Lawrence N J, Liu C Y, McGown A T, Zhang X. Isolation of E-1-(4'-Hydroxyphenyl)-but-1-en-3-one from Scutellaria barbata[J]. Planta Medica, 1996,62(2): 185—186.
[44] Cha Y Y, Lee E O, Lee H J, Park Y D, Ko S G, Kim D H, Kim H M, Kang I C, Kim S H. Methylene chloride fraction of Scutellaria barbata induces apoptosis in human U937 leukemia cells via the mitochondrial signaling pathway[J]. Clinica Chimica Acta, 2004.348(1): 41—48.
[45] Yu J, Liu H, Lei J, Tan W, Hu X, Zou G. Antitumor activity of chloroform fraction of Scutellaria barbata and its active constituents[J]. Phytotherapy Research, 2007,21(9): 817—822.
[46] 郭丽华,齐聪,杨红,樊零范,张勤华. 半枝莲黄酮类单体对人卵巢癌 SKOV3 细胞增殖的影响[J]. 上海中医药杂志, 2013(1): 61—65.
[47] Tang P M K, Chan J Y W, Zhang D M, Au S W N, Fong W P, Kong S K, Tsui S K W, Waye M M Y, Mak T C W, Fung K P. Pheophorbide a, an active component in Scutellaria barbata, reverses P-glycoprotein-mediated multidrug resistance on a human hepatoma cell line R-HepG2[J]. Cancer Biology and Therapy, 2007,6(4): 504—509.
[48] 叶华,郭蒙,吴琼,朱宇珍,郑学宝. 半枝莲多糖对C26荷瘤小鼠 caspase-3, 8, 9 活性的影响[J]. 中国老年学杂志, 2012,32(23): 5152—5153.
[49] Yin X, Zhou J, Jie C, Xing D, Zhang Y. Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549[J]. Life Sciences, 2004,75(18): 2233—2244.
[50] Bui Xuan N H, Tang P M K, Wong C K, Fung K P. Photo-activated pheophorbide-a, an active component of Scutellaria barbata, enhances apoptosis via the suppression of ERK-mediated autophagy in the estrogen receptor-negative human breast adenocarcinoma cells MDA-MB-231[J]. Journal of Ethnopharmacology, 2010,131(1): 95—103.
[51] Song X, Yao J, Wang F, Zhou M, Zhou Y, Wang H, Wei L, Zhao L, Li Z, Lu N. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein[J]. Toxicology and Applied Pharmacology, 2013,271(2): 144—155.
[52] Wei L, Lin J, Xu W, Cai Q, Shen A, Hong Z, Peng J. Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer[J]. International Journal of Molecular Sciences, 2012,13(8): 9419—9430.
[53] 王桂玲,房建强,边书芹,崔召娟,赵雪梅. 半枝莲中总生物碱的提取及抑菌作用的初步研究[J]. 中成药, 2013,35(6): 1315—1319.
[54] Sato Y, Suzaki S, Nishikawa T, Kihara M, Shibata H, Higuti T. Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus[J]. Journal of Ethnopharmacology, 2000,72(3): 483—488.
[55] 孙明礼,付会鹏,张静. 半枝莲多糖脱色及清除羟基自由基作用的研究[J]. 离子交换与吸附, 2008,24(4): 305—312.
[56] 杨容,王志,习洋,冯涛. 中药半枝莲中黄酮类化合物的抗氧化活性[J]. 河北大学学报(自然科学版), 2007,27(5): 489—491.
[57] 赵杰,孙设宗,官守涛,张红梅. 半枝莲多糖对四氯化碳致小鼠肝损伤保护作用的研究[J]. 中国中医药科技, 2012,19(1): 39—40.
[58] Zhang G H, Wang Q, Chen J J, Zhang X M, Tam S C, Zheng Y T. The anti-HIV-1 effect of scutellarin[J]. Biochemical and Biophysical Research Communications, 2005,334(3): 812—816.
[59] 张志发,李成韶,程丽芳. 半枝莲化淤排石汤治疗泌尿系结石的研究[J]. 山东中医杂志, 1991(2): 6.
