›› 2016, Vol. 45 ›› Issue (02): 107-111.DOI: 10.3969/j.issn.1009-7791.2016.02.002

• 植物生理生化与分子生物学 • 上一篇    下一篇

枇杷花茶水提物的镇咳、抗炎与抗氧化作用研究

林国清,何恩铭,王雅英,杨伟琪,张亚楠   

  1. (1.厦门医学院,福建 厦门 361008;2.福建省道地药材生物工程重点实验室,福建 厦门 361008;3.厦门市道地药材生物工程重点实验室,福建 厦门 361008;4.福建省亚热带植物研究所,福建省亚热带植物生理生化重点实验室,福建 厦门 361006)
  • 收稿日期:2016-02-05 修回日期:2016-08-14 出版日期:2016-06-10 发布日期:2016-06-10
  • 通讯作者: 张亚楠
  • 作者简介:林国清,副教授,从事中医与中药学研究。
  • 基金资助:
    厦门市科技计划项目(3502Z20133045、3502Z20131004、3502Z20151245)

Study on Antitussive, Anti-inflammatory and Antioxidant Effects of Aqueous Extracts of Loquat Flower Tea

LIN Guo-qing,HE En-ming,WANG Ya-ying,YANG Wei-qi,ZHANG Ya-nan   

  1. (1.Xiamen Medical College, Xiamen 361008, Fujian China; 2.Fujian Provincial Key Laboratory of Genuine Regional Drug Bio-Engineering, Xiamen 361008, Fujian China; 3.Xiamen Key Laboratory of Biotechnology of Chinese Traditional Medicine, Xiamen 361008, Fujian China; 4.Fujian Key Laboratory of Subtropical Plant Physiology and Biochemistry, Fujian Institute of Subtropical Botany, Xiamen 361006, Fujian China )
  • Received:2016-02-05 Revised:2016-08-14 Online:2016-06-10 Published:2016-06-10
  • Contact: ZHANG Ya-nan

摘要: 采用小鼠氨水致咳法研究枇杷花茶水提物镇咳效果,以二甲苯致小鼠耳肿胀法研究其抗炎效果,并从枇杷花茶的还原能力及对超氧阴离子和羟自由基的清除作用分析枇杷花茶水提物的抗氧化效果。结果表明,枇杷花茶的水提物高剂量组(3000 mg·kg-1)、低剂量组(700 mg·kg-1)均有镇咳抗炎效果,水提物的浓度越高,效果越好。各浓度枇杷花茶水提物均表现出一定的还原能力,对于羟基自由基和超氧阴离子都有一定的清除效果。其中,20 mg·mL-1水提物还原效果最好(吸光值0.903),超过0.2 mg·mL-1抗坏血酸(吸光值0.814);10 mg·mL-1的水提物对超氧阴离子的清除率为47.32%;20 mg·mL-1水提物对于羟基自由基的清除效果非常明显,清除率为91.62%。枇杷花茶水提物镇咳、抗炎、抗氧化效果明显。

关键词: 枇杷花茶, 镇咳, 抗炎, 抗氧化

Abstract: The antitussive, anti-inflammatory and antioxidant function of loquat flower tea were studied by the methods of cough of mice stimulated by ammonia, xylene-induced ear acute inflammatory and scavenging capability of superoxide anion free radical and hydroxyl free radical, total antioxidant capability. The results showed that both high dose group (3000 mg穔g-1) and low dose group (700 mg穔g-1) of loquat flower tea had antitussive and anti-inflammatory effect, with high doses more effective. All concentrations of water extract showed certain reduction capacities, and had scavenging effects on hydroxyl free radical and superoxide anion. The water extract (20 mg穖L-1) had the best effect (absorbance value 0.903), better than 0.2 mg穖L-1 VC (absorbance value 0.814). The scavenging rate to superoxide anion of the 10 mg穖L -1 water extract was 47.32%, and the scavenging effect on hydroxyl radical of 20 mg穖L-1 water extract was obvious, which was 91.62%. The water extract of loquat tea had strong antitussive and anti-inflammatory, antioxidant effect.

Key words: loquat flower tea, antitussive function, anti-inflammatory function, antioxidant function

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