石斛多糖的结构修饰与生物活性研究进展

doi:10.3969/j.issn.1009-7791.2026.03.012

亚热带植物科学 ›› 2026, Vol. 55 ›› Issue (3): 378-384.DOI: 10.3969/j.issn.1009-7791.2026.03.012

石斛多糖的结构修饰与生物活性研究进展

陈菲，陈淳，许传俊，明艳林^*

(福建省亚热带植物研究所 / 福建省亚热带植物生理生化重点公共实验室，福建厦门 361006)

收稿日期:2026-04-07 接受日期:2026-06-03 出版日期:2026-06-30 发布日期:2026-06-30
通讯作者: 明艳林
基金资助:
厦门市自然科学基金项目(3502Z202473102)；福建省亚热带植物研究所基本科研项目(3502Z2025YZS04)

Research Progress in Structure Modification and Bioactivities of Dendrobium Polysaccharide

CHEN Fei, CHEN Chun, XU Chuan-jun, MING Yan-lin^*

(Fujian Key Laboratory of Subtropical Plant Physiology and Biochemistry / Fujian Institute of Subtropical Botany, Xiamen 361006, Fujian China)

Received:2026-04-07 Accepted:2026-06-03 Online:2026-06-30 Published:2026-06-30
Contact: MING Yan-lin

摘要/Abstract

摘要： 石斛多糖是石斛主要的活性成分之一，具有抗氧化、增强免疫和降血糖等功效。石斛多糖的生物活性与其结构有着密切关系，原本复杂的大分子结构导致其水溶性低、黏度高，选择合适的结构修饰方法对石斛多糖生物活性的有效发挥及产品的开发具有重要的促进作用。本文总结近年来国内外对石斛多糖结构修饰研究的进展，重点介绍修饰对石斛多糖的结构及生物活性的影响，探讨结构特征与生物活性之间的内在联系，以期为石斛多糖的深度开发与应用提供参考。

关键词: 石斛多糖, 结构修饰, 生物活性, 构效关系

Abstract: Dendrobium polysaccharide is one of the major bioactive constituents of Dendrobium, with significant antioxidant, immunomodulatory and hypoglycemic activities. Its bioactivities are closely correlated with its structural characteristics. However, the inherent complex macromolecular architecture leads to low water solubility and high viscosity, which greatly restrict its practical applications. Therefore, the selection of suitable structural modification strategies is of great importance to improve the bioactivities of Dendrobium polysaccharides and facilitate their product development. This paper reviews the recent progress in structural modification of Dendrobium polysaccharides, focusing on the influences of different modification approaches on the structures and bioactivities of polysaccharides. In addition, the structure-activity relationships of Dendrobium polysaccharides are discussed, aiming to provide valuable references for the further development and application of Dendrobium polysaccharides.

Key words: Dendrobium polysaccharide, structure modification, bioactivity, structure-activity relationship

中图分类号:

Q946.3

陈菲, 陈淳, 许传俊, 明艳林. 石斛多糖的结构修饰与生物活性研究进展[J]. 亚热带植物科学, 2026, 55(3): 378-384.

CHEN Fei, CHEN Chun, XU Chuan-jun, MING Yan-lin. Research Progress in Structure Modification and Bioactivities of Dendrobium Polysaccharide[J]. Subtropical Plant Science, 2026, 55(3): 378-384.

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石斛多糖的结构修饰与生物活性研究进展

Research Progress in Structure Modification and Bioactivities of Dendrobium Polysaccharide

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