Research Progress of PAL Gene and Its Function in Medicinal Plants

doi:10.3969/j.issn.1009-7791.2024.02.012

Subtropical Plant Science ›› 2024, Vol. 53 ›› Issue (2): 181-190.DOI: 10.3969/j.issn.1009-7791.2024.02.012

• Review • Previous Articles

Research Progress of PAL Gene and Its Function in Medicinal Plants

WANG Ruo-xian1, ZHU Rui-yan1, KAI Guo-yin1*, SHI Min1*

(1. School of Pharmacy, Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang China)

Received:2024-03-19 Accepted:2024-04-05 Online:2024-04-30 Published:2024-05-27
Contact: KAI Guo-yin, SHI Min

药用植物PAL基因及其功能研究进展

王若娴1，朱瑞艳1，开国银1*，时敏1*

(浙江中医药大学药学院，浙江省药食植物活性成分与健康国际科技合作基地，浙江杭州 311400)

通讯作者: 开国银，时敏
基金资助:
浙江省农业(中药材新品种选育)新品种选育重大科技专项课题(2021C02074-3)；浙江省自然科学基金(LQ23H280010)

Abstract

Abstract: The phenylalanine metabolic pathway is a key metabolic pathway in plants, producing compounds such as flavonoids, phenolic acids, and lignans. These substances not only regulate plant growth, development, and stress resistance, but also employ in the prevention and treatment of diseases, which are major factors in determining the quality of medicinal plants. Phenylalanine ammonia-lyase (PAL) is the catalyst for the first reaction in the phenylalanine metabolic pathway and is the key and rate-limiting enzyme of this pathway. This review examines the fundamental features, control of expression of the PAL gene in medicinal plants, which serves as a foundation for further understanding the role of PAL in medicinal plants.

Key words: medicinal plants, phenylpropane metabolic pathway, phenylalanine ammonia-lyase, gene expression and regulation

摘要： 苯丙烷代谢途径是植物主要代谢途径之一，可产生黄酮、酚酸和木质素类等物质，这些物质不仅参与调控植物生长发育和抗逆等生理活动，还被用于预防和治疗疾病，是决定药用植物品质的关键因素之一。苯丙氨酸解氨酶(phenylalanine ammonia-lyase，PAL)负责催化苯丙烷类代谢途径中第一个反应，是此途径的关键酶和限速酶。本文就药用植物中PAL基因的基本特性、表达调控机制等方面的研究进行综述，为进一步阐明药用植物中PAL的功能提供参考依据。

关键词: 药用植物, 苯丙烷代谢途径, 苯丙氨酸解氨酶, 基因表达与调控

CLC Number:

Q943

WANG Ruo-xian, ZHU Rui-yan, KAI Guo-yin, SHI Min. Research Progress of PAL Gene and Its Function in Medicinal Plants[J]. Subtropical Plant Science, 2024, 53(2): 181-190.

王若娴, 朱瑞艳, 开国银, 时敏. 药用植物PAL基因及其功能研究进展[J]. 亚热带植物科学, 2024, 53(2): 181-190.

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Research Progress of PAL Gene and Its Function in Medicinal Plants

药用植物PAL基因及其功能研究进展

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