Multi-omics Research Progress on the Active Ingredients Biosynthesis and Regulation in Dendrobium officinale

doi:10.3969/j.issn.1009-7791.2024.04.013

Subtropical Plant Science ›› 2024, Vol. 53 ›› Issue (4): 381-388.DOI: 10.3969/j.issn.1009-7791.2024.04.013

• Review • Previous Articles

Multi-omics Research Progress on the Active Ingredients Biosynthesis and Regulation in Dendrobium officinale

LIU Li-qing, GUO Chi-ming*, SHI Jian-yu, GUO Ying, MENG Hong-yan, ZENG Xin-ping

(Fujian Institute of Subtropical Botany / Fujian Key Laboratory of Subtropical Plant Physiology and Biochemistry, Xiamen 361006, Fujian China)

Received:2023-12-13 Accepted:2024-05-16 Published:2024-11-20
Contact: GUO Chi-ming

铁皮石斛活性成分生物合成与调控多组学研究进展

刘黎卿，郭迟鸣*，施建羽，郭莺，孟红岩，曾新萍

(福建省亚热带植物研究所 / 福建省亚热带植物生理生化重点实验室，福建厦门 361006)

通讯作者: 郭迟鸣
基金资助:
厦门市重大科技计划项目(3502Z20211003)

Abstract

Abstract: Dendrobium officinale, an important medicinal plant in the Dendrobium genus of Orchidaceae, is rich in active metabolites such as polysaccharides, alkaloids and flavonoids. The biosynthesis, regulation and accumulation of plant metabolites is a complex process. In recent years, omics technologies such as genomics, transcriptomics, proteomics, and metabolomics have developed rapidly, providing a deeper understanding of the multi-level regulatory network of D. officinale metabolites from different dimensions such as transcription, post transcription, translation, and epigenetics. This article reviews the multi-omics research progress on the active ingredients biosynthesis and regulation in D. officinale, and prospects the future research directions, which can provide theoretical basis for molecular breeding, cultivation management and industrial application of D. officinale.

Key words: Dendrobium officinale; omics research; active ingredients; biosynthesis; regulation mechanism

摘要： 铁皮石斛Dendrobium officinale是兰科石斛属重要的药用植物，富含多糖、生物碱和黄酮等活性代谢产物。植物代谢产物的生物合成、调控及积累是一个复杂的过程，近年来基因组、转录组、蛋白质组以及代谢组等组学技术飞速发展，从转录、转录后、翻译以及表观遗传等不同维度更深入地解析铁皮石斛代谢产物多层次调控网络。本文综述了国内外各类组学在铁皮石斛活性成分生物合成与调控的研究进展，并对未来研究的方向进行了展望，以期为铁皮石斛的分子育种、栽培管理及产业应用提供理论依据。

关键词: 铁皮石斛；组学研究；活性成分；生物合成途径；调控机制

CLC Number:

Q945

LIU Li-qing, GUO Chi-ming, SHI Jian-yu, GUO Ying, MENG Hong-yan, ZENG Xin-ping. Multi-omics Research Progress on the Active Ingredients Biosynthesis and Regulation in Dendrobium officinale[J]. Subtropical Plant Science, 2024, 53(4): 381-388.

刘黎卿，郭迟鸣，施建羽，郭莺，孟红岩，曾新萍. 铁皮石斛活性成分生物合成与调控多组学研究进展[J]. 亚热带植物科学, 2024, 53(4): 381-388.

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Multi-omics Research Progress on the Active Ingredients Biosynthesis and Regulation in Dendrobium officinale

铁皮石斛活性成分生物合成与调控多组学研究进展

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