Advances on Chemical Constituents and Biological
Activities of Griffonia

doi:10.3969/j.issn.1009-7791.2026.02.010

Subtropical Plant Science ›› 2026, Vol. 55 ›› Issue (2): 226-235.DOI: 10.3969/j.issn.1009-7791.2026.02.010

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Advances on Chemical Constituents and Biological Activities of Griffonia

HE Fan^1,2, LIU Shao-song², ZHENG Zhi-zhong², CHE Xiao-rong^1,2, LIN He-tong¹, MING Yan-lin^1,2*

(1. College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian China; 2. Fujian Institute of Subtropical Botany / Plant Introduction & Quarantine and Plant Product Key Laboratory of Xiamen City, Xiamen 361006, Fujian China)

Received:2025-08-14 Accepted:2025-11-11 Online:2026-04-30 Published:2026-04-30
Contact: MING Yan-lin

加纳籽属植物化学成分与生物活性研究进展

何帆^1,2，刘韶松²，郑志忠²，车小榕^1,2，林河通¹，明艳林^1,2*

(1. 福建农林大学食品科学学院，福建福州 350002；2. 福建省亚热带植物研究所 / 厦门市植物引种检疫与植物源产物重点实验室，福建厦门 361006)

通讯作者: 明艳林
基金资助:
厦门市重大科技计划项目(3502Z2024YZS01)

Abstract

Abstract: Griffonia is an ancient genus in the family Fabaceae, with only four species distributed in West African countries including Ghana, Côte d'Ivoire and Togo. The current study of this genus focuses on the Griffonia simplicifolia, whose seeds have a high content of the antidepressant active ingredient 5-hydroxytryptophan (5-HTP), as well as other alkaloids, flavonoids, and unsaturated fatty acid classes, which have antidepressant, anticancer, antimicrobial, anti-inflammatory, antioxidant, and other bioactivities. In this paper, we review this genus from the aspects of chemical constituent and biological activities, with a view to providing reference for exploring the biosynthesis and exploitation research of 5-HTP.

Key words: Griffonia, chemical constituents, biological activities

摘要： 加纳籽属Griffonia是豆科中一个起源古老的属，目前仅发现有4种，均分布于西非的加纳、科特迪瓦和多哥等国家和地区。该属植物目前研究主要集中于非洲加纳籽Griffonia simplicifolia，其种子有高含量的抗抑郁活性成分5-羟基色氨酸（5-HTP），以及其他生物碱、黄酮和不饱和脂肪酸类等成分，具有抗抑郁、抗癌、抗菌、抗炎、抗氧化等生物活性。本文从化学成分、生物活性等方面对该属植物进行综述，以期为5-HTP生物合成和开发利用研究提供参考。

关键词: 加纳籽属, 化学成分, 生物活性

CLC Number:

Q946.8

HE Fan, LIU Shao-song, ZHENG Zhi-zhong, CHE Xiao-rong, LIN He-tong, MING Yan-lin. Advances on Chemical Constituents and Biological Activities of Griffonia[J]. Subtropical Plant Science, 2026, 55(2): 226-235.

何帆, 刘韶松, 郑志忠, 车小榕, 林河通, 明艳林. 加纳籽属植物化学成分与生物活性研究进展[J]. 亚热带植物科学, 2026, 55(2): 226-235.

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Advances on Chemical Constituents and Biological Activities of Griffonia

加纳籽属植物化学成分与生物活性研究进展

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