Abstract: In this study, three extraction methods were carried out to explore the effects of Pseudostellaria heterophylla crude extracts on antioxidant, whitening and moisturizing. The results indicated that the crude extracts by water revealed highest inhibiting rates than those of ethanol and supercritical fluid extraction in ABTS, DPPH free radicals and reactive oxygen species. According to the analysis of whitening, the crude extract by ethanol and water extraction methods was the best in the inhibiting rate of B16 cell melanin content and tyrosinase activity, respectively. Further, crude polysaccharide from P. heterophylla was performed in hygroscopic rate and moisturizing analysis. The results showed that crude polysaccharide had good moisturizing and moisture absorption efficiency, which was close to hyaluronic acid. In addition, the evaluation of skin water loss also revealed a very significant preventation.

Key words: Pseudostellaria heterophylla, crude polysaccharide, antioxidant, whitening, moisturizing

摘要： 比较三种不同萃取方式对太子参Pseudostellaria heterophylla粗提物抗氧化、美白、保湿等方面的影响。结果显示，在ABTS和DPPH自由基及细胞内活性氧(ROS)抑制率分析中，以水萃方式所得粗提物的抑制效果最佳，优于醇萃取及超临界流体萃取。在美白功效方面，B16细胞黑色素含量抑制率以醇萃物最佳，酪氨酸酶活性抑制率则以水萃物最佳。进一步萃取太子参粗多糖体分析其保湿及吸湿效果，结果显示太子参粗多糖体具有良好的保湿及吸湿功效，其效果与透明质酸相近，应用于皮肤水分散失率评估，也具有显著的预防功效。

关键词: 太子参, 粗多糖体, 抗氧化, 美白, 保湿